I have been reviewing JavaScript frameworks. I have not been satisfied with the popular frameworks. I recently started looking at Durandal. It is based on Require.js so it is easy to create modules to organize your code. From what I have read, you do not have to start from a base durandal object. You just work with POJO (plain old javascript objects). That way you can also use your modules in non-durandal code as well. This is definitely a framework I am going to spend more time investigating.